Эпигенетика - [53]

11: 1640-1650.

Greiner D., BonaldiT., Eskeland R., RoemerE., and ImhofA. 2005. Identification of a specific inhibitor of the histone methyltrans­ferase SU(VAR)3-9. Nat. Chem. Biol.1: 143-145.

Grewal S.I. and Klar A.J. 1996. Chromosomal inheritance of epi­genetic states in fission yeast during mitosis and meiosis. Cell86: 95-101.

Grozinger C.M. and Schreiber S.L. 2002. Deacetylase enzymes: Biological functions and the use of small molecule inhibitors. Chem. Biol.9: 3-16.

Guarente L. and Picard E 2005. Calorie restriction — The SIR2 connection. Cell120: 473-482.

Hall I.M., Shankaranarayana G.D., Noma K., Ayoub N., Cohen A., and Grewal S.L. 2002. Establishment and maintenance of a heterochromatin domain. Science297: 2232-2237.

Hanahan D. and Weinberg R.A. 2000. The hallmarks of cancer. Cell100: 57-70.

Harvey A.C. and Downs J .A. 2004. What functions do linker histones provide? Mol. Microbiol. 53: 771-775.

Hassan A.H., Prochasson P., Neely K.E., Galasinski S.C., Chandy M., Carrozza M.J., and Workman J.L. 2002. Function and se­lectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell111: 369-379.

Heard E. 2005. Delving into the diversity of facultative heterochro­matin: The epigenetics of the inactive X chromosome. Curr. Opin. Genet. Dev.15: 482-489.

Henikoff S. 2005. Histone modifications: Combinatorial complex­ity or cumulative simplicity? Proc. Natl. Acad. Sci.102: 5308- , 5309.

Henikoff S. and Ahmad K. 2005. Assembly of vanant histones into chromatin. Annu Rev. Cell Dev. Biol.21: 133-153.

Herr A.J., Jensen M.B., DalmayT., and Baulcombe D.C. 2005. RNA polymerase IV directs silencing of endogenous DNA. Science308: 118-120.

Hirota T., Lipp J.J., Toh B.H., and Peters J.M. 2005. Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature438: 1176-1180.

Hochedlinger K., Blelloch R., Brennan C, Yamada Y, Kim M., Chin L., and Jaenisch R. 2004. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev.18: 1875-1885.

Holbert M.A. and Marmorstein R. 2005. Structure and activity of enzymes that remove histone modifications. Curr. Opin. Struct. Biol. 15: 673-680. Holliday R. 1994. Epigenetics: An overview. Dev. Genet.15: 453-457.

Ishii K.J. and Akira S. 2005. TLR ignores methylated RNA? Im­munity23: 111-113.

Jackson J.P., Lindroth A.M., CaoX., and Jacobsen S.E. 2002. Con­trol of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature416: 556-560.

Jacobson R.H., Ladumer A.G., King D.S. andTjian R. 2000. Struc­ture and function of a human TAFII250 double bromodomain module. Science.288: 1422-1425.

Jaenisch R. and Bird A. 2003. Epigenetic regulation of gene expres­sion: How the genome integrates intrinsic and environmental signals. Nat. Genet, (suppl.) 33: 245-254.

Janicki S.M., Tsukamoto T., Salghetti S.E., Tansey W.P., Sachidanan- dam R., Prasanth K.V., Ried T., Shav-Tal Y., Bertrand E., Singer R.H., and Spector D.L. 2004. From silencing to gene expression: Real-time analysis in single cells. Cell116: 683-698.

Jeddeloh J.A., Stokes..L., and Richards E.J. 1999. Maintenance of genomic methylation requires a SWI2/SNF2-like protein. Nat. Genet.22: 94-97.

Jenuwein T. and Allis C.D. 2001. Translating the histone code. Sci­ence293: 1074-1080.

Jones RA. and Martienssen R. 2005. A blueprint for a Human Epigenome Project: The AACR Human Epigenome Workshop. Cancer Res.65: 11241-11246.

Kanellopoulou C, Muljo S.A., Kung A.L., Ganesan S., Drapkin R., Jenuwein T., Livingston D.M., and Rajewsky K. 2005. Dicer- deficient mouse embryonic stem cells are defective in differentia­tion and centromeric silencing. Genes Dev.19: 489-501.

Kayne P.S., Kim U.J., Han M., Mullen J.R., Yoshizaki E, and Grunstein M. 1988. Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast. Cell55: 27- 39.

Khochbin S. 2001. Histone HI diversity: Bridging regulatory signals to linker histone function. Gene271: 1-12.

Khorasanizadeh S. 2004. The nucleosome: From genomic organiza­tion to genomic regulation. Cell116: 259-272.

Kim J., Daniel J., Espejo A., Lake A., Krishna M., Xia L., Zhang Y., and Bedford M.X. 2006. Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Rep.4: 397-403.

Kimmins S. and Sassone-Corsi P. 2005. Chromatin remodeling and epigenetic features of germ cells. Nature434: 583-589.

KlarAJ. 1998. Propagating epigenetic states through meiosis: Where Mendel’s gene is more than a DNA moiety. Trends Genet.14: 299-301.

KlarAJ. 2004. An epigenetic hypothesis for human brain laterality, handedness, and psychosis development. Cold Spring Harbor Symp. Quant. Biol.69: 499-506.

Knoepfler P.S., ZhangX.-Y., Cheng R.E., Gafken P.R., McMahon S.B., and Eisenman R.N 2006. Myc influences global chromatin structure. EMBO J.25: 2723-2734.

Komberg R.D. 1974. Chromatin structure: A repeating unit of his­tones and DNA. Science184: 868-871.

Lachner M., O’Sullivan R.J., and Jenuwein T 2003. An epigenetic road map for histone lysine methylation.